Dr. Maciej J. Stawikowski

Dr. Stawikowski

Assistant Scientist
Department of Chemistry and Biochemistry
Ph.D. University of Gdansk, Poland

Contact Information
Office: PS 310
Phone: (561) 297-4871
Email: mstawikowski@fau.edu

Research Interests

  • Development of novel membrane interacting lipid probes for neuroscience and cancer research
  • Development of solvatochromic amino acid mimetics to study peptide-membrane interactions
  • Drug design & synthesis of biologically active compounds (peptides & peptidomimetics)
  • Enzymology of proteases and their inhibitors in cancer

 

Recent Publications 

Thomas D, Rubio V, Iragavarapu V, Guzman E, Pelletier OB, Alamgir S, Zhang Q, Stawikowski MJ. Solvatochromic and pH-Sensitive Fluorescent Membrane Probes for Imaging of Live Cells. ACS Chem Neurosci. 2021 Feb 17;12(4):719-734. doi: 10.1021/acschemneuro.0c00732

Rubio V., Iragavarapu V., Stawikowski M.J. Synthesis and Characterization of ROSA Dye - A Rhodamine B-type Fluorophore, Suitable for Bioconjugation and Fluorescence Studies in Live Cells. Protein Pept Lett. 2019;26(10):758-767.

Cudic, P., N. Joshi, D. Sagher, B. T. Williams, M. J. Stawikowski and H. Weissbach (2016). "Identification of activators of methionine sulfoxide reductases A and B." Biochem Biophys Res Commun 469(4): 863-867.

Fields, G. B. and M. J. Stawikowski (2016). "Imaging Matrix Metalloproteinase Activity Implicated in Breast Cancer Progression." Methods Mol Biol 1406: 303-329.

Stawikowski, M. J., R. Stawikowska and G. B. Fields (2015). "Collagenolytic Matrix Metalloproteinase Activities toward Peptomeric Triple-Helical Substrates." Biochemistry 54(19): 3110-3121.

Krzywda, S., M. Jaskolski, K. Rolka and M. J. Stawikowski (2014). "Structure of a proteolytically resistant analogue of (NLys)5SFTI-1 in complex with trypsin: evidence for the direct participation of the Ser214 carbonyl group in serine protease-mediated proteolysis." Acta Crystallogr D Biol Crystallogr 70(Pt 3): 668-675.

 Stawikowski, M. J., B. Aukszi, R. Stawikowska, M. Cudic and G. B. Fields (2014). "Glycosylation modulates melanoma cell alpha2beta1 and alpha3beta1 integrin interactions with type IV collagen." J Biol Chem 289(31): 21591-21604.

 

Awards and Recognition

  • Early Career Reviewer Program Participant at the Center for Scientific Review, NIH, 2016 - present