Publications

Selected Publications (PubMed; GoogleScholar )

  • MOLECULES

Implications of Mucin-Type O-Glycosylation in Alzheimer's Disease.

  1. Vela Navarro, G. De Nadai Mundim, M. Cudic Molecules 2025 30(9):1895.

DOI: 10.3390/molecules30091895.

Molecules

  • CHEMBIOCHEM

Synthesis and Thermodynamic Evaluation of Sialyl-Tn MUC1 Glycopeptides Binding to Macrophage Galactose-Type Lectin.

  1. Ayyalasomayajula,I. Boneva, D. Ormaza, A. Whyte, Jr., K. Farook, Z. Gorlin, E. Yancey, S. André, H. Kaltner, and M. Cudic ChemBioChem 2024 25: e202400391.

DOI: 10.1002/cbic.202400391

Chembiochem Chembiochem

 

  • CANCERS

Targeting Siglec-Sialylated MUC1 Immune Axis in Cancer.

  1. Ayyalasomayajula, and M. Cudic Cancers (Basel), 2024 16:1334. DOI: 10.3390/cancers16071334

Cancers

 

  • ANTIBODIES (BASEL)

Preventative Cancer Vaccine-Elicited Human Anti-MUC1 Antibodies Have Multiple Effector Functions.

M.L. McKeague, J. Lohmueller, M.T. Dracz, N. Saadallah, E.D. Ricci, D.M. Beckwith, R. Ayyalasomayajula, M. Cudic, O.J. Finn Antibodies (Basel) 2024, 13(4):85.
DOI: 10.3390/antib13040085

Cancers

 

  • FRONTIERS IN CHEMISTRY

Mucin-type O-Glycosylation Proximal to β-Secretase Cleavage Site Affects APP Processing and Aggregation Fate.
Y. Singh, D. Regmi, D. Ormaza, R. Ayyalasomayajula, N. Vela, G. Mundim, D. Du, D. Minond, M. Cudic Front. Chem. 2022, 10:859822.
DOI: 10.3389/fchem.2022.859822

 

  • EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Exploring Glycan Binding Specificity of Odorranalectin by Alanine Scanning Library.
Y. Singh, P. Cudic, M. Cudic Eur. J. of Org. Chem. 2022, 2022(28):e202200302.
DOI: 10.1002/ejoc.202200302

 

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

 

  • BIOCHEMISTRY

Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin.
D.M. Beckwith, F.G. FitzGerald, M.C. Rodriguez Benavente, E.R. Mercer, A.K. Ludwig, M. Michalak, H. Kaltner, J. Kopitz, H.-J. Gabius, M. Cudic Biochemistry 2021, 60:547–558.
DOI: 10.1021/acs.biochem.0c00942

BIOCHEMISTRY

 

  • ACS CHEMICAL NEUROSCIENCE

Tyrosine O-GalNAc Alters the Conformation and Proteolytic Susceptibility of APP Model Glycopeptides.
Y. Singh, D. Ormaza, A. Massetti, D. Minond, M. Cudic ACS Chem. Neurosci. 2021, 12:2974–2980.
DOI: 10.1021/acschemneuro.1c00387

 

ACS CHEMICAL NEUROSCIENCE

  • GLYCOCONUGATE JOURNAL

TF-containing MUC1 glycopeptides fail to entice Galectin-1 recognition of tumor-associated Thomsen-Freidenreich (TF) antigen (CD176) in solution.
F.G. FitzGerald, M.C. Rodriguez Benavente, C. Garcia, Y. Rivero, Y. Singh, H. Wang, G.B. Fields, M. Cudic Glycoconj. J. 2020, 37(6):657–666.
DOI: 10.1007/s10719-020-09951-x

 

  • SEMINARS IN IMMUNOLOGY

Tumor-associated O-glycans of MUC1: Carriers of the glyco-code and targets for cancer vaccine design.
D.M. Beckwith, M. Cudic Semin. Immunol. 2020, 47:101389.
DOI: 10.1016/j.smim.2020.101389

 

  • JOURNAL OF ORGANIC CHEMISTRY

Positional Scanning MUC1 Glycopeptide Library Reveals the Importance of PDTR Epitope Glycosylation for Lectin Binding.Y. Singh, M.C. Rodriguez Benavente, M.H. Al-Huniti, D. Beckwith, R. Ayyalasomayajula, E. Patino, W.S. Miranda, A. Wade, M. Cudic J. Org. Chem. 2020, 85(3):1434–1445.
DOI: 10.1021/acs.joc.9b02396 

 

JOURNAL OF ORGANIC CHEMISTRY

  • AMINO ACIDS

Targeting cancer-specific glycans by cyclic peptide lectinomimics.
M.C. Rodriguez, A.B. Yongye, M. Cudic, K. Martinez Mayorga, E. Liu, B.M. Mueller, J. Ainsley, T. Karabencheva-Christova, C.Z. Christov, M. Cudic, P. Cudic Amino Acids 2017, 49(11):1867–1883.
DOI: 10.1007/s00726-017-2485-3

 

  • NATURE SCIENTIFIC REPORTS

Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential.
J.J. Lohmueller, S. Sato, L. Popova, I.M. Chu, M.A. Tucker, R. Barberena, G.M. Innocenti, M. Cudic, J.D. Ham, W.C. Cheung, R.D. Polakiewicz, O.J. Finn Sci. Rep. 2016, 6:31740.
DOI: 10.1038/srep31740 

  • BIOCHEMISTRY

Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.
M.C. Rodriguez, S. Yegorova, J.P. Pitteloud, A.E. Chavaroche, S. André, A. Ardá, D. Minond, J. Jiménez-Barbero, H.J. Gabius, M. Cudic Biochemistry 2015, 54(29):4462–4474.
DOI: 10.1021/acs.biochem.5b00555

 

Biochemistry

  • ANALYTICAL BIOCHEMISTRY

Development of an AlphaScreen assay for discovery of inhibitors of low-affinity glycan-lectin interactions.
S. Yegorova, A.E. Chavaroche, M.C. Rodriguez, D. Minond, M. Cudic Anal. Biochem. 2013, 439(2):123–131.
DOI: 10.1016/j.ab.2013.04.028