Galectin-Glycan Interactions: Guidelines for Monitoring by 77 Se NMR Spectroscopy, and Solvent (H2 O/D2 O) Impact on Binding.
Diercks T, Medrano FJ, FitzGerald FG, Beckwith D, Pedersen MJ, Reihill M, Ludwig AK, Romero A, Oscarson S, Cudic M, Gabius HJ. Chemistry. 2021 27(1):316-325.
doi: 10.1002/chem.202003143.
TF-containing MUC1 glycopeptides fail to entice Galectin-1 recognition of tumor-associated Thomsen-Freidenreich (TF) antigen (CD176) in solution.
FitzGerald FG, Rodriguez Benavente MC, Garcia C, Rivero Y, Singh Y, Wang H, Fields GB, Cudic M. Glycoconj J. 2020 37(6):657-666. doi: 10.1007/s10719-020-09951-x.
Influence of protein (human galectin-3) design on aspects of lectin activity.
García Caballero G, Beckwith D, Shilova NV, Gabba A, Kutzner TJ, Ludwig AK, Manning JC, Kaltner H, Sinowatz F, Cudic M, Bovin NV, Murphy PV, Gabius HJ. Histochem Cell Biol. 2020 154(2):135 153. doi: 10.1007/s00418-020-01859-9.
Tumor-associated O-glycans of MUC1: Carriers of the glyco-code and targets for cancer vaccine design.
Beckwith DM, Cudic M. Semin Immunol. 2020 47:101389. doi: 10.1016/j.smim.2020.101389.
Positional Scanning MUC1 Glycopeptide Library Reveals the Importance of PDTR Epitope Glycosylation for Lectin Binding.
Singh Y, Rodriguez Benavente MC, Al-Huniti MH, Beckwith D, Ayyalasomayajula R, Patino E, Miranda WS, Wade A, Cudic M. J Org Chem. 2020 85(3):1434-1445. doi: 10.1021/acs.joc.9b02396.
Targeting cancer-specific glycans by cyclic peptide lectinomimics.
Rodriguez MC, Yongye AB, Cudic M, Martinez Mayorga K, Liu E, Mueller BM, Ainsley J, Karabencheva-Christova T, Christov CZ, Cudic M, Cudic P. Amino Acids. 2017 49(11):1867-1883. doi: 10.1007/s00726-017-2485-3.
Antibodies elicited by the first non-viral prophylactic cancer vaccine show tumor-specificity and immunotherapeutic potential.
Lohmueller JJ, Sato S, Popova L, Chu IM, Tucker MA, Barberena R, Innocenti GM, Cudic M, Ham JD, Cheung WC, Polakiewicz RD, Finn OJ. Sci Rep. 2016 6:31740. doi: 10.1038/srep31740.
Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.
Rodriguez MC, Yegorova S, Pitteloud JP, Chavaroche AE, André S, Ardá A, Minond D, Jiménez-Barbero J, Gabius HJ, Cudic M. Biochemistry. 2015 54(29):4462-74. doi: 10.1021/acs.biochem.5b00555.
Development of an AlphaScreen assay for discovery of inhibitors of low-affinity glycan-lectin interactions.
Yegorova S, Chavaroche AE, Rodriguez MC, Minond D, Cudic M. Anal Biochem. 2013 439(2):123-31. doi: 10.1016/j.ab.2013.04.028.
